Use the link below to share a full-text version of this article with your friends and colleagues. There are no easy answers, but I try to be honest with them and not sugar-coat things. But I am also their protector. Implementation and integration of the clinic into the existing institutional structures required collaboration and cooperation with clinical trial units, nursing administration, and creation of new positions. Building a relationship with both the child and the parent makes the process a little easier and less scary for everyone. Stem cells are special human cells that have the potential to develop into almost any type of cell. : manuscript writing; P.G., J.T. Some procedures include viral vector infusions for in vivo targeted stem cell sites and others require preparative chemotherapy for lymphodepletion. has research funding from California Institute for Regenerative Medicine grants. In addition, the ASCC Network maintains a portfolio of preclinical projects to guide and accelerate basic and translational research. The process used by SCCG originated in Korea and yields extremely high numbers of stem cells. Abbreviations: ASCC, Alpha Stem Cell Clinic; CAR, chimeric antigen receptor; CVI, Competency Validation Inventory; HCT, hematopoietic cell transplantation; QRG, Quick Reference Guide. For this reason, the California Institute for Regenerative Medicine has formed a network of clinics called the Alpha Stem Cell Clinics Network. They have a lot of what-if questions. Although we are a “for-profit” organization, our goal is not to patent stem cell technology for corporate profit but rather to learn the medical potential of these cells and contribute to the science of regenerative medicine. Since the treatment methods used in these novel stem cell‐based trials likely will be part of any eventual “package insert” describing instructions for outpatient use of the approved product, it made sense to test them in the actual site of such eventual therapy. 1). The CVI, developed at COH by its Nursing Professional Practice Leader Group for stem cell transplantation, provides an inventory of validated nursing skills that are actionable, modified to specific ASCC nursing activities, and include human research protection training, as well as patient management of possible and expected side effects. A parent can’t always be at the child’s bedside. Our website has a list of the protocols we have that are currently active for the investigational use of stem cells. The PCC is the bridge connecting the research participant with clinic nurses and research staff, personalizing the patient's journey by developing necessary education materials. ASCC also offered other support for trial implementation, including patient scheduling, education, and navigation, biospecimen processing, and regulatory assistance, all of which are essential aspects for accelerating stem cell clinical studies. There have been no cases reported of adult mesenchymal stem cells contributing to tumor formation. This article was published online on 03 November 2017. The California Institute for Regenerative Medicine (CIRM) proposed the concept of an Alpha Stem Cell Clinic (ASCC), also known as Alpha Clinic, in 2012. “The longer I’m here, the broader the scope of treatments we at Boston Children’s/Dana Farber Cancer and Blood Disorders Center offer children. Stem cell therapy, also known as regenerative medicine, promotes the repair response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. Establishing a stem cell clinic comes with challenges, but integration into the existing clinical and research structures is feasible, and nursing competencies play a crucial role in the success of this process. Stem Cell Transplantation is last chance for some patients and they enter the unit highly hopeful for their life. At COH, we have capitalized on the existing highly trained personnel involved in management of cell products and the delivery of patient‐centric care for hematopoietic cell transplantation (HCT). I work up to four 12-hour shifts per week, usually with two patients per shift, depending on acuity. In one example, patients suffering from heart attacks have been given their own fat derived stem cells so they could speed up repair of the heart muscle and indeed, these patients have shown quicker healing compared to those not given real stem cells. After discharge, ASCC patients are provided a card that identifies and prioritizes their status as ASCC patients. 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